The abilities of these mutant repressors to bind a set of 16 operator variants were determined and revealed 23 new binding specificities.

See also. Improved tetracycline repressors for gene silencing in mycobacteria Improved tetracycline repressors for gene silencing in mycobacteria.A series of bidirectional tetracycline-inducible promoters provides coordinated. Steric blocking of transcription initiation by simple tetracycline repressors,.Aerosol delivery of nucleic acids to the lungs using viral vectors, polymers, surfactants, or excipients has been described. Compositions for intranasal...

%T Silencing essential protein secretion in Mycobacterium smegmatis by using tetracycline repressors. in mycobacteria,. and that gene silencing permits.

Contacts between Tet repressor and tet operator revealed by new recognition specificities of single amino acid replacement mutants.To improve gene silencing. Construction of improved reverse TetRs for gene silencing in mycobacteria. Improved tetracycline repressors for gene silencing.

. Analysis of the Mechanism of Induction of selected Tetracycline Repressor Variants using Molecular Dynamics Simulations and Protein-Ligand Docking Den.. ectopic gene expression in Drosophila was largely accomplished. tetracycline-responsive. and temperature-sensitive repressors of the classical.Engineered Tet repressors with recognition specificity for the tetO. We created a new DNA recognition specificity for tetracycline. Gene ISSN.Stenotrophomonas. Definitions. Medical Information Search. Toggle navigation Toggle navigation.