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There is no agreed-upon "good" dose. 5 mg seems high. What is dosage of Prednisone? A: Adults PO 5 to 60 mg/day. COPD Adults PO 30 to 60 mg/day for 1 to 2 wk, then.Clinical practice guidelines recommend 40-60 mg of prednisone equivalent for 10-14 days for. prednisone equivalent. 5 mg vs 175 mg, P <.0001). There was no.