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EUCREAS/ICANDRA, fixed -dose vildagliptin/metformin combination, should. treated with a maximum dosage of 1000 mg of metformin administered twice per day.

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TRANSPARENCY COMMITTEE OPINION. EUCREAS 50 mg/1000 mg, tablet Box of 60 (CIP: 382 770-5). The maximum recommended dose of metformin is 3 g per day.” 3.

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The maximum recommended daily dose is 120 mg. other antidiabetic agents (insulins, acarbose,metformin, thiazolidinediones, dipeptidyl peptidase-4.